FACA/FANCA Products

Antibodies
FACA/FANCA Antibody
FACA/FANCA Antibody
NBP1-03286
Species: Hu, Pm
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
FACA/FANCA Antibody
FACA/FANCA Antibody
NB100-2564
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
FACA/FANCA Antibody
FACA/FANCA Antibody
AF6026
Species: Hu
Applications: WB
Host: Goat Polyclonal
Lysates
FACA/FANCA Overexpression Lys ...
FACA/FANCA Overexpression Lysate (...
H00002175-T01
Species: Hu
Applications: WB
FACA/FANCA Overexpression Lys ...
FACA/FANCA Overexpression Lysate (...
NBP2-08666
Applications: WB
Proteins
FACA/FANCA Recombinant Protei ...
FACA/FANCA Recombinant Protein
H00002175-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
FACA/FANCA RNAi
FACA/FANCA RNAi
H00002175-R02
Species: Hu
FACA/FANCA RNAi
FACA/FANCA RNAi
H00002175-R01
Species: Hu

Description

FANCA (Fanconi anemia group A) protein is a DNA repair protein that may function as a cell cycle checkpoint or in postreplication repair. FANCA may also be important for the maintenance of chromosome stability and reparation of interstrand DNA cross linkages.

Defects in FANCA result in Fanconi Anemia, a genetically heterogeneous autosomal recessive disorder characterized by progressive pancytopenia, diverse congenital malformations, and a predisposition to develop malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair. At the cellular level FANCA defects cause a hypersensitivity to DNA-damaging agents, chromosomal instability, and defective DNA repair.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2175
Alternate Names
  • FA
  • Protein FACA
  • FANCH
  • Fanconi anemia, type 1
  • FAH
  • Fanconi anemia, complementation group H
  • FA-H
  • FACAFanconi anemia group A protein
  • FAAMGC75158
  • FA1
  • Fanconi anemia, complementation group A

Research Areas for FACA/FANCA

Find related products by research area and learn more about each of the different research areas below.

Cancer
DNA Repair
Genes Sensitive to DNA Damaging Agents

PTMs for FACA/FANCA

Learn more about PTMs related to FACA/FANCA.

Phosphorylation
Ubiquitination
Methylation
Cleavage
Demethylation
Reduction

Bioinformatics Tool for FACA/FANCA

Discover related pathways, diseases and genes to FACA/FANCA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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