EZH1 Products

Description

EZH1 is a human homolog of the Drosophila gene Enhancer of zeste E(z), a member of the polycomb group of transcriptional repressors. In mice, EZH1 is a regulator of homeotic gene expression implicated in the assembly of repressive protein complexes in chromatin. The strong sequence conservation between species suggests potential role for EZH1 in human development as a transcriptional regulator and as a component of protein complexes that stably maintain heterochromatin.

Bioinformatics

Entrez	14055 Mouse 2145 Human
Uniprot	AAC50778 Human NP_001982.2 Human Q92800 Human
Product By Gene ID	2145
Alternate Names	EC 2.1.1.43 enhancer of zeste homolog 1 (Drosophila) Enhancer of zeste homolog 1 ENX-2 histone-lysine N-methyltransferase EZH1 KIAA0388enhancer of zeste (Drosophila) homolog 1 KMT6B

Research Areas for EZH1

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Chromatin Research

Related EZH1 Blog Posts

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EZH1 has more to offer than gene repression EZH1 is part of the Polycomb-group family of proteins, which are responsible for remodeling chromatin in genes and modulating epigenetic silencing during development.  Specifically, EZHI is a component of PRC2, or polycomb repressive complex-2.  PR...    Read more.

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