EVI-1 Products

Description

EVI1 (ecotropic viral integration site 1) was originally identified as a gene located in the integration site of ecotropic retroviruses in the mouse genome that resulted in myeloid tumors. EVI1 is a zinc finger transcription factor that plays an important role in development and leukemogenesis. It is an oncogene that can have effects on cell proliferation, differentiation, and apoptosis. Chromosomal translocations involving EVI1 result in chronic myelogenous leukemia (CML). Alternate names for EVI1 include AML1-EVI-1 fusion protein, PRDM3, and MDS1-EV1.

Bioinformatics

Entrez	14013 Mouse 2122 Human 4197 Human
Uniprot	NM_005241 Human NP_001098547.3 Human NP_001098548 Human NP_001098548.2 Human NP_004982 Human NP_005232 Human Q03112 Human Q13465 Human
Product By Gene ID	2122
Alternate Names	AML1-EVI-1 fusion protein AML1-EVI-1 ecotropic viral integration site 1 Ecotropic virus integration site 1 protein homolog EVI-1 EVI1MDS1-EVI1 MDS1 and EVI1 complex locus protein EVI1 MDS1 and EVI1 complex locus protein MDS1 MDS1 and EVI1 complex locus MDS1 MGC163392 MGC97004 Myelodysplasia syndrome 1 protein myelodysplasia syndrome 1 Myelodysplasia syndrome-associated protein 1 oncogene EVI1 PRDM3 zinc finger protein Evi1