ERCC1 Products

Antibodies
ERCC1 Antibody (1A3)
ERCC1 Antibody (1A3)
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
ERCC1 Antibody (CL1284)
ERCC1 Antibody (CL1284)
NBP2-34480
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC
Host: Mouse Monoclonal
Lysates
ERCC1 Overexpression Lysate ( ...
ERCC1 Overexpression Lysate (Native)
NBL1-10319
Applications: WB
ERCC1 Overexpression Lysate ( ...
ERCC1 Overexpression Lysate (Native)
NBL1-10318
Applications: WB
ERCC1 Overexpression Lysate ( ...
ERCC1 Overexpression Lysate (Denat...
H00002067-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human ERCC1 Prote ...
Recombinant Human ERCC1 Protein
H00002067-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human ERCC1 Prote ...
Recombinant Human ERCC1 Protein
H00002067-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human ERCC1 Prote ...
Recombinant Human ERCC1 Protein
NBP1-98981
Species: Hu
Applications: PAGE
RNAi
ERCC1 RNAi
ERCC1 RNAi
H00002067-R02
Species: Hu
Applications: RNAi, RNAi SP
ERCC1 RNAi
ERCC1 RNAi
H00002067-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1 XPF complex makes the 5'incision. Elevated levels of ERCC1 have also been reported in Cisplatin resistant cells.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2067
Alternate Names
  • DNA excision repair protein ERCC-1
  • UV20
  • COFS4
  • RAD10
  • excision repair cross-complementing rodent repair deficiency, complementationgroup 1 (includes overlapping antisense sequence)

Research Areas for ERCC1

Find related products by research area and learn more about each of the different research areas below.

Cancer
DNA Repair
Nucleotide Excision Repair

Bioinformatics Tool for ERCC1

Discover related pathways, diseases and genes to ERCC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related ERCC1 Blog Posts

Check out the latest blog posts on ERCC1.
Beta Tubulin III and neurogenesis
Beta tubulin III, also known as Tuj-1, is a class III member of the beta tubulin protein family. Beta tubulins are one of two structural components that form our microtubule network. While general tubulins play a role in a wide range of cellular pr...    Read more.
53BP1 - a marker for DNA Double Strand Break
53BP1 (p53 binding protein 1) was originally thought to be an enhancer for p53 transcriptional, but later studies have demonstrated that it is actually a substrate for ataxia telangiectasia mutated (ATM). 53BP1 is a classic late DNA damage response...    Read more.
53BP1 - DNA damage is no fun
The 53BP1 (p53 binding protein 1) was initially believed to be a p53 transcriptional enhancing partner, but it has now been established as an ataxia telangiectasia mutated (ATM) substrate. As a late DNA damage response (DDR) marker, 53BP1 appears duri...    Read more.
Using PCNA as an Antibody Marker
PCNA antibodies are useful biomarkers in DNA repair studies. PCNA is one of several proteins essential for the completion of nucleotide excision repair, a multi-stage process involving 20 - 30 proteins, and an important factor in repairing damage and...    Read more.
NER Antibodies in Cancer Research
We at Novus Biologicals have over 230 products in our antibody catalog devoted to nucleotide excision repair. NER is a multi-stage sequential process involving over 30 proteins, all of which have been widely studied. Being the primary method to repair...    Read more.
Read more ERCC1 related blogs.