EPS15 Products

Description

EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. EPS15 may be phosphorylated on tyrosine 849 following DNA damage, resulting in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute myelogeneous leukemias, resulting in a rogue activator protein, so EPS15 antibodies may be useful for cancer research.

Bioinformatics

Entrez	13858 Mouse 2060 Human 313474 Rat
Uniprot	EP15_HUMAN Human NM_001981 Human NP_001972.1 Human P42566 Human
Product By Gene ID	2060
Alternate Names	AF1P AF-1P ALL1 fused gene from chromosome 1 epidermal growth factor receptor pathway substrate 15 epidermal growth factor receptor substrate 15 MLLT5 Protein AF-1p Protein Eps15

Research Areas for EPS15

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Signal Transduction