Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Rt, Bv, Xp, Ze
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Description
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiatortRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex.Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound toeIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round ofinitiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
1968 |
| Alternate Names |
- EIF2
- eIF-2gA
- eIF-2-gamma X
- EIF2gamma
- EIF2Geukaryotic translation initiation factor 2, subunit 3 (gamma, 52kD)
- eIF-2gX
- eukaryotic translation initiation factor 2 subunit 3
- Eukaryotic translation initiation factor 2 subunit gamma X
- eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
- eukaryotic translation initiation factor 2G
|
