EGF-L6 Products

Description

The EGFL6 gene encodes an epidermal growth factor-like protein 6 with isoform 1 having 553 amino acids in length at 61 kDA and isoform 2 at 554 amino acids in length at 61 kDA. Member sof the epidermal growth factor (EGF) repeat family are known to be involved in the regulation of cell cycle, proliferation, and developmental processes. This protein encourages matrix assembly and aids in binding integrin alpha-8/beta-1, playing a role in hair follicle morphogenesis and is known to interact with genes SH3GL3 and SH3GL2. EGFL6 has been linked to detrusor sphincter dyssynergia, benign meningioma, bladder diverticulum, lung meningioma, and obesity.

Bioinformatics

Entrez	25975 Human
Uniprot	AAH38587 Human Q8IUX8 Human NP_056322 Human
Product By Gene ID	25975
Alternate Names	MAM and EGF domains-containing gene protein epidermal growth factor-like protein 6 EGF-like protein 6 EGF repeat-containing protein 6 MAEG W80 MAM and EGF domain containing DKFZp564P2063 EGF-like-domain, multiple 6

Diseases related to EGF-L6

Discover more about diseases related to EGF-L6.

Tissue Adhesions
Malignant Neoplasms
Neoplasms
Tumor Angiogenesis
Lung Neoplasms
Malignant Neoplasm Of Ovary
Osteoporosis
Bone Diseases
Liver Carcinoma
Liver Neoplasms
Stomach Neoplasms
Bone Necrosis
Malignant Neoplasm Of Lung
Carcinoma
Fracture
Cardiovascular Diseases
Mammary Neoplasms
Epithelial Ovarian Cancer
Ovarian Neoplasm

Pathways for EGF-L6

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Angiogenesis
Cell Adhesion
Hair Follicle Morphogenesis
Hair Follicle Development
Blood Coagulation
Cell Migration
Glycosylation
Endothelial Cell Migration
Regeneration
Coagulation
Cell Cycle
Fibrinolysis
Bone Development
Liver Regeneration
Wound Healing
Pathogenesis
Oncogenesis
Secretion

Research Areas for EGF-L6

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Cell Cycle and Replication

PTMs for EGF-L6

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Phosphorylation
Glycosylation

Bioinformatics Tool for EGF-L6

Discover related pathways, diseases and genes to EGF-L6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.