EBP Products

Antibodies
EBP Antibody
EBP Antibody
NBP1-85699
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
EBP Antibody
EBP Antibody
NBP1-59782
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
EBP Overexpression Lysate (Na ...
EBP Overexpression Lysate (Native)
NBL1-10094
Applications: WB
Proteins
EBP Recombinant Protein Antig ...
EBP Recombinant Protein Antigen
NBP1-85699PEP
Species: Hu
Applications: AC
RNAi
EBP RNAi
EBP RNAi
H00010682-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The protein encoded by the EBP gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist (3H)emopamil and the photoaffinity label (3H)azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome). (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 10682
Alternate Names
  • CDPX2
  • Emopamil-binding protein
  • D8-D7 sterol isomerase
  • EC 5.3.3.5
  • Delta(8)-Delta(7) sterol isomerase
  • sterol 8-isomerase
  • Cholestenol Delta-isomerase
  • CPXDX-linked dominant (Happle syndrome)
  • delta-7-isomerase
  • CPX3-beta-hydroxysteroid-delta-8
  • Delta(7)-isomerase
  • 3-beta-hydroxysteroid-Delta(8)
  • emopamil binding protein (sterol isomerase)

Bioinformatics Tool for EBP

Discover related pathways, diseases and genes to EBP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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