EAAT1/GLAST-1/SLC1A3 Products

Antibodies
EAAT1/GLAST-1/SLC1A3 Antibody ...
EAAT1/GLAST-1/SLC1A3 Antibody
Species: Hu, Mu, Rt, Bv
Applications: WB, ELISA, Flow, Flow-IC, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
EAAT1/GLAST-1/SLC1A3 Antibody ...
EAAT1/GLAST-1/SLC1A3 Antibody
NBP1-42587
Species: Hu, Mu, Rt, Bv
Applications: WB, ICC/IF, IHC-P
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
EAAT1/GLAST-1/SLC1A3 Antibody ...
EAAT1/GLAST-1/SLC1A3 Antibody
AF6048
Species: Hu
Applications: WB, IHC
Host: Sheep Polyclonal
Lysates
EAAT1/GLAST-1/SLC1A3 Overexpr ...
EAAT1/GLAST-1/SLC1A3 Overexpressio...
NBP2-10257
Applications: WB
EAAT1/GLAST-1/SLC1A3 Overexpr ...
EAAT1/GLAST-1/SLC1A3 Overexpressio...
H00006507-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human EAAT1/GLAST ...
Recombinant Human EAAT1/GLAST-1/SL...
H00006507-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human EAAT1/GLAST ...
Recombinant Human EAAT1/GLAST-1/SL...
H00006507-P01
Species: Hu
Applications: WB, ELISA, PA
EAAT1/GLAST-1/SLC1A3 Recombin ...
EAAT1/GLAST-1/SLC1A3 Recombinant P...
NBP1-84939PEP
Species: Hu
Applications: AC
RNAi
EAAT1/GLAST-1/SLC1A3 RNAi
EAAT1/GLAST-1/SLC1A3 RNAi
H00006507-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Human excitatory amino acid transporters (EAATs) are members of a family of high affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system. It is believed that these proteins reduce extracellular glutamate concentration, thereby modulating synaptic signaling. In addition, EAATs may also be important for the prevention of glutamate excitotoxicity. EAAT1 is prominently expressed in the frontal cortex, hippocampus and basal ganglia and is also reported to be found in heart, placenta, lung and striated muscle. EAAT1 shares some pharmacological similarities with EAAT3 and both are potent antagonists that appear to specifically block transport mediated by EAAT2. EAAT1 transports L-glutamate and also L- and D-aspartate, acting as a symport by co-transporting sodium. EAAT1 is essential for terminating the postsynaptic action of glutamate, by rapidly removing released glutamate from the synaptic cleft.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Rat
Product By Gene ID 6507
Alternate Names
  • excitatory amino acid transporter 1
  • Sodium-dependent glutamate/aspartate transporter 1
  • EA6FLJ25094
  • GLASTGLAST1
  • EAAT1GLAST-1
  • Solute carrier family 1 member 3
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3

Research Areas for EAAT1/GLAST-1/SLC1A3

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers

PTMs for EAAT1/GLAST-1/SLC1A3

Learn more about PTMs related to EAAT1/GLAST-1/SLC1A3.

Biotinylation
Phosphorylation
Carboxylation
Glycosylation
Oxidation
Reduction
Nitration
Cleavage
Acetylation
Deglycosylation

Bioinformatics Tool for EAAT1/GLAST-1/SLC1A3

Discover related pathways, diseases and genes to EAAT1/GLAST-1/SLC1A3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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