DYRK1A Products

Antibodies
DYRK1A Antibody (7D10)
DYRK1A Antibody (7D10)
H00001859-M01
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IP
Host: Mouse Monoclonal
DYRK1A Antibody [Unconjugated ...
DYRK1A Antibody [Unconjugated]
AF5407
Species: Hu, Rt
Applications: WB, Simple Western, IHC
Host: Sheep Polyclonal
DYRK1A Antibody
DYRK1A Antibody
NBP1-84031
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
DYRK1A Overexpression Lysate ...
DYRK1A Overexpression Lysate (Native)
NBP2-05742
Applications: WB
Proteins
DYRK1A Recombinant Protein An ...
DYRK1A Recombinant Protein Antigen
NBP1-84032PEP
Species: Hu
Applications: AC
DYRK1A Recombinant Protein An ...
DYRK1A Recombinant Protein Antigen
NBP1-84031PEP
Species: Hu
Applications: AC
DYRK1A Recombinant Protein
DYRK1A Recombinant Protein
NBP2-51732
Species: Rt
Applications: PAGE
RNAi
DYRK1A RNAi
DYRK1A RNAi
H00001859-R08
Species: Hu
DYRK1A RNAi
DYRK1A RNAi
H00001859-R07
Species: Hu
DYRK1A RNAi
DYRK1A RNAi
H00001859-R10
Species: Hu

Description

DYRK1A encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 1859
Alternate Names
  • MNBEC 2.7.110EC 2.7.12
  • DYRK1
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

Research Areas for DYRK1A

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Protein Kinase

Bioinformatics Tool for DYRK1A

Discover related pathways, diseases and genes to DYRK1A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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