Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Ca, Bv
Applications: ELISA
Host: Goat Polyclonal
Species: Hu
Applications: AC
Description
DTX1, also known as E3 ubiquitin-protein ligase DTX1, is a 67.4 kDa, 620 amino acid protein that is involved in regulating the Notch pathway by monitoring ubiquitination and stimulating the breakdown of MEKK1. Current research is being conducted with diseases and disorders such as osteosarcoma, Noonan syndrome, and neuronitis. The protein interacts in disease and Notch signaling pathways with CRK, ITCH, UBE2D2, UBE2D3, and UBC.
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human Human |
| Product By Gene ID |
1840 |
| Alternate Names |
- deltex homolog 1 (Drosophila)
- Deltex1
- deltex1
- hDTX1
- hDx-1
- protein deltex-1
|
Research Areas for DTX1
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction