DRP1 Products

Antibodies
DRP1 Antibody (3B5)
DRP1 Antibody (3B5)
H00010059-M01
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, S-ELISA
Host: Mouse Monoclonal
Lysates
DRP1 Overexpression Lysate
DRP1 Overexpression Lysate
NBL1-09967
Species: Hu
Applications: WB
DRP1 Overexpression Lysate
DRP1 Overexpression Lysate
NBL1-09966
Species: Hu
Applications: WB
Proteins
Recombinant Human DRP1 GST (N ...
Recombinant Human DRP1 GST (N-Term...
H00010059-P01
Species: Hu
Applications: WB, ELISA, Func, ICC/IF, In vitro, IP, PA, AP, MS
DRP1 Antibody Blocking Peptid ...
DRP1 Antibody Blocking Peptide
NB110-55288PEP
Species: Hu
Applications: AC
DRP1 Recombinant Protein Anti ...
DRP1 Recombinant Protein Antigen
NBP2-34205PEP
Species: Hu
Applications: AC

Description

DRP1 is a member of the dynamin GTPase superfamily, which that contributes to mitochondrial division in mammalian cells. DRP1 plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses. Therefore, DRP1 provides a genetic tool to assess the role of mitochondria at synapses.

The DRP1 gene has 3 alternatively spliced transcripts encoding different isoforms, which are alternatively polyadenylated.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 10059
Alternate Names
  • Dynamin-related protein 1
  • Dynamin-like protein
  • Dynamin-like protein IV
  • HdynIV
  • Dynamin-like protein 4
  • Dymple
  • Dynamin family member proline-rich carboxyl-terminal domain less
  • dynamin-1-like protein
  • VPS1
  • FLJ41912
  • HDYNIV
  • DYMPLEDYNIV-11
  • DVLPEC 3.6.5.5
  • DRP1Dnm1p/Vps1p-like protein
  • DLP1
  • dynamin 1-like

Research Areas for DRP1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cell Biology
Mitochondrial Fusion Proteins
Neurodegeneration
Neuroscience
Signal Transduction

Bioinformatics Tool for DRP1

Discover related pathways, diseases and genes to DRP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related DRP1 Blog Posts

Check out the latest blog posts on DRP1.
Understanding Mitophagy Mechanisms: Canonical PINK1/Parkin, LC3-Dependent Piecemeal, and LC3-Independent Mitochondrial Derived Vesicles
By Christina Towers, PhD What is Mitophagy?The selective degradation of mitochondria via double membrane autophagosome vesicles is called mitophagy. Damaged mitochondria can generate harmful amounts of reactive ox...    Read more.

    Read more.
Dynamin-related Protein 1 (DRP1) in Mitochondria and Apoptosis.
Dynamin-related Protein 1 (DRP1) is known to function in mitochondrial and peroxisomal division and mediate membrane fission through oligomerization into ring-like structure and sever the mitochondrial membrane, through a GTP hydrolysis-dependent mech...    Read more.
Read more DRP1 related blogs.