DPM1 Products

Description

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. (provided by RefSeq)

Bioinformatics

Entrez	8813 Human
Uniprot	AAH08466.1 Human NM_003859 Human NP_003850 Human NP_003850.1 Human O60762 Human
Product By Gene ID	8813
Alternate Names	CDGIEEC 2.4.1.83 dolichol monophosphate mannose synthase dolichol-phosphate mannosyltransferase Dolichyl-phosphate beta-D-mannosyltransferase dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit DPM synthase Mannose-P-dolichol synthase MPD synthase MPDSDolichol-phosphate mannose synthase