DPH5 Products

Antibodies
DPH5 Antibody
DPH5 Antibody
NBP2-13934
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
DPH5 Antibody
DPH5 Antibody
H00051611-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Lysates
DPH5 Overexpression Lysate (D ...
DPH5 Overexpression Lysate (Denatu...
H00051611-T01
Species: Hu
Applications: WB
DPH5 Overexpression Lysate (N ...
DPH5 Overexpression Lysate (Native)
NBP2-07112
Applications: WB
Proteins
DPH5 Recombinant Protein
DPH5 Recombinant Protein
H00051611-P01
Species: Hu
Applications: WB, ELISA, PA
DPH5 Recombinant Protein Anti ...
DPH5 Recombinant Protein Antigen
NBP2-13934PEP
Species: Hu
Applications: AC

Description

DPH5 encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 51611
Alternate Names
  • HSPC143
  • protein x 0011
  • EC 2.1.1.98
  • diphthine synthase
  • Diphthamide biosynthesis methyltransferase
  • NPD015
  • CGI-30
  • MGC61450
  • DPH5 homolog (S. cerevisiae)

Diseases related to DPH5

Discover more about diseases related to DPH5.

Diphtheria
Neoplasms
Polydactyly
Radial Polydactyly
Poisoning

Pathways for DPH5

View related products by pathway and learn more about each of the pathways below.

Translation
Methylation
Trna Modification
Localization

Research Areas for DPH5

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

PTMs for DPH5

Learn more about PTMs related to DPH5.

Amidation
Methylation
Ribosylation

Bioinformatics Tool for DPH5

Discover related pathways, diseases and genes to DPH5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.