DNAM-1/CD226 Products

Antibodies
DNAM-1/CD226 Antibody (102511 ...
DNAM-1/CD226 Antibody (102511) [Un...
MAB666
Species: Hu
Applications: WB, Flow, CyTOF-ready, Neut
Host: Mouse Monoclonal
DNAM-1/CD226 Antibody
DNAM-1/CD226 Antibody
NBP1-85001
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
DNAM-1/CD226 Antibody [Unconj ...
DNAM-1/CD226 Antibody [Unconjugated]
AF666
Species: Hu
Applications: WB, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
DNAM-1/CD226 Overexpression L ...
DNAM-1/CD226 Overexpression Lysate...
NBL1-08922
Applications: WB
Proteins
DNAM-1/CD226 Recombinant Prot ...
DNAM-1/CD226 Recombinant Protein A...
NBP1-85001PEP
Species: Hu
Applications: AC
Recombinant Human DNAM-1/CD22 ...
Recombinant Human DNAM-1/CD226 Pro...
NBP2-53072
Species: Hu
Applications: PAGE
Recombinant Human DNAM-1/CD22 ...
Recombinant Human DNAM-1/CD226 Pro...
NBP2-22746
Species: Hu
Applications: PAGE
RNAi
DNAM-1/CD226 RNAi
DNAM-1/CD226 RNAi
H00010666-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

CD226 is a 65kD type I transmembrane glycoprotein, known as DNAM-1 (DNAX accessory molecule-1), PTA1(platelet and T cell activation antigen 1), or TLiSA1 (T lineage-specific activation antigen 1 antigen). It belongs to immunoglobulin superfamily containing 2 Ig-like domains, is expressed on majority of T lymphocytes, NK cells, monocytes, platelets, and a subset of B cells, activated endothelial cells. DNAM-1 is also expressed on CD8+ (but not CD8-) dendritic cells in mouse model. CD226 is an adhesion molecule involved in CTL and NK cell-mediated cytotoxicity. It has been identified that CD155 (poliovirus receptor, PVR) and CD112 (nectin-2, PRR-2) are CD226 ligands. DX11 antibody is able to inhibit CTL and NK cell-mediated cytotoxicity, and to block T cell cytokine production.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 10666
Alternate Names
  • TLiSA1
  • T lineage-specific activation antigen 1 antigen
  • PTA1
  • CD226 antigenplatelet and T cell activation antigen 1
  • DNAM-1DNAX accessory molecule-1
  • DNAM1adhesion glycoprotein
  • DNAX accessory molecule 1
  • CD226 molecule

PTMs for DNAM-1/CD226

Learn more about PTMs related to DNAM-1/CD226.

Phosphorylation
Dephosphorylation

Bioinformatics Tool for DNAM-1/CD226

Discover related pathways, diseases and genes to DNAM-1/CD226. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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