DNAJC2 Products

Description

This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq]

Bioinformatics

Product By Gene ID	27000
Alternate Names	DnaJ (Hsp40) homolog, subfamily C, member 2 dnaJ homolog subfamily C member 2 MPHOSPH11M-phase phosphoprotein 11 MPP11Zuotin-related factor 1 ZRF1zuotin ZUO1 zuotin related factor 1

Research Areas for DNAJC2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Immunology
Signal Transduction