DIO1 Products

Antibodies
DIO1 Antibody (1E4)
DIO1 Antibody (1E4)
H00001733-M01
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Proteins
DIO1 Recombinant Protein
DIO1 Recombinant Protein
H00001733-P01
Species: Hu
Applications: WB, ELISA, PA
DIO1 Partial Recombinant Prot ...
DIO1 Partial Recombinant Protein
H00001733-Q01
Species: Hu
Applications: WB, ELISA, PA

Description

Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs. Dio-1 translocates to the nucleus, and activates apoptosis during limb development. Programmed cell death, a highly regulated form of apoptosis, plays an important role in determining the amount of tissue, the shape, and the definition of each digit during limb development. Dio-1 expression is upregulated when an apoptotic signal is detected, and subsequently apoptosis is induced. This process is similar to the expression of NFkappaB and NGF in response to external signals. Dio-1 expression is suppressed by caspase inhibitors and Bcl-2 expression. This supports the theory that Dio-1 functions in the onset of programmed cell death.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 1733
Alternate Names
  • EC 1.97.1.10
  • EC 1.97.1
  • DIOI
  • ITDI1
  • 5DI
  • type I iodothyronine deiodinase
  • Type-I 5'-deiodinase
  • thyroxine deiodinase type I (selenoprotein)
  • Type 1 DI
  • TXDI1MGC130051
  • MGC130050
  • deiodinase, iodothyronine, type I

PTMs for DIO1

Learn more about PTMs related to DIO1.

Deiodination
Phosphorylation
Carboxylation
Glycosylation
Acetylation
Bromination

Bioinformatics Tool for DIO1

Discover related pathways, diseases and genes to DIO1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.