DAP Kinase 1 Products

Antibodies
DAP Kinase 1 Antibody
DAP Kinase 1 Antibody
NBP2-30083
Species: Hu, Mu
Applications: WB, ICC/IF, IHC-P
Host: Rabbit Polyclonal
DAP Kinase 1 Antibody
DAP Kinase 1 Antibody
NBP2-38580
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
DAP Kinase 1 Antibody
DAP Kinase 1 Antibody
NBP2-38468
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
DAP Kinase 1 Overexpression L ...
DAP Kinase 1 Overexpression Lysate...
NBL1-09716
Applications: WB
Proteins
Recombinant Human DAP Kinase ...
Recombinant Human DAP Kinase 1 Pro...
H00001612-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human DAP Kinase ...
Recombinant Human DAP Kinase 1 Pro...
H00001612-P01
Species: Hu
Applications: WB, ELISA, PA
DAP Kinase 1 Recombinant Prot ...
DAP Kinase 1 Recombinant Protein A...
NBP2-38580PEP
Species: Hu
Applications: AC
RNAi
DAP Kinase 1 RNAi
DAP Kinase 1 RNAi
H00001612-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

DAPK1 (Death-associated protein kinase 1) is a calmodulin dependent serine/threonine serine kinase which functions as a positive mediator of gamma-interferon induced programmed cell death. DAPK1 expression is frequently lost in human carcinomas and B-cell leukemia, and lower levels of expression correlates with high rates of metastasis. The loss of DAPK expression provides a link between suppression of apoptosis and metastasis. DAPK1 is thought be involved in an early apoptotic checkpoint which eliminates premalignant cells from cancer formation. Studies in bladder cancer patients have also shown that hypermethylation of DAPK1 correlates to high recurrence rates and thus DAPK1 may be used as a prognostic marker. DAPK1 is also reportedly a molecular regulator of neuronal death in epilepsy.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 1612
Alternate Names
  • EC 2.7.11.1
  • EC 2.7.11
  • DAPKDAP kinase 1
  • DKFZp781I035
  • death-associated protein kinase 1

Research Areas for DAP Kinase 1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Phospho-Specific

PTMs for DAP Kinase 1

Learn more about PTMs related to DAP Kinase 1.

Methylation
Phosphorylation
Demethylation
Cleavage
Dephosphorylation
Acetylation

Bioinformatics Tool for DAP Kinase 1

Discover related pathways, diseases and genes to DAP Kinase 1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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