CSN7b Products

Description

Component of the COP9 signalosome complex (CSN), is a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Bioinformatics

Entrez	64708 Human
Uniprot	NP_073567 Human NP_073567.1 Human Q9H9Q2 Human
Product By Gene ID	64708
Alternate Names	Arabidopsis, homolog) subunit 7B COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) COP9 signalosome complex subunit 7b CSN7BMGC111077 FLJ12612 Signalosome subunit 7b

Research Areas for CSN7b

Find related products by research area and learn more about each of the different research areas below.

Growth and Development
Neuronal Cell Markers
Neurotransmission
Signal Transduction
Transcription Factors and Regulators