CRTH-2/GPR44 Products

Antibodies
CRTH-2/GPR44 Antibody
CRTH-2/GPR44 Antibody
NBP1-76755
Species: Hu, Mu, Rt, GP
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
CRTH-2/GPR44 Antibody
CRTH-2/GPR44 Antibody
NBP1-50452
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC-P
Host: Rabbit Polyclonal
Lysates
CRTH-2/GPR44 Overexpression L ...
CRTH-2/GPR44 Overexpression Lysate...
NBL1-11281
Applications: WB
Proteins
CRTH-2/GPR44 Peptide
CRTH-2/GPR44 Peptide
NBP1-76755PEP
Species: Hu
Applications: AC
CRTH-2/GPR44 Peptide
CRTH-2/GPR44 Peptide
NBP1-76756PEP
Species: Hu
Applications: AC
RNAi
CRTH-2/GPR44 RNAi
CRTH-2/GPR44 RNAi
H00011251-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells. CRTH2 has been reported to be expressed in the central nervous system, peripheral tissues, and in blood cells, particularly activated T helper-2 cells. Two transcripts have been isolated, a 3.5-kb transcript expressed primarily in the thalamus, frontal cortex, pons, and hippocampus, and a 3.4-kb transcript expressed in fetal liver, leukocytes, and thymus. ESTs have been isolated from B-cell/lung/testis, brain, kidney, liver/spleen, placenta, prostate, testis, and thymus libraries.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 11251
Alternate Names
  • Chemoattractant receptor-homologous molecule expressed on Th2 cells
  • CD294 antigen
  • DP2
  • putative G-protein coupled receptor 44
  • CD294
  • CRTH2chemoattractant receptor homologous molecule expressed on T helper type 2 cells
  • DL1R
  • G protein-coupled receptor 44

Research Areas for CRTH-2/GPR44

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GPCR

Bioinformatics Tool for CRTH-2/GPR44

Discover related pathways, diseases and genes to CRTH-2/GPR44. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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