CRM1 Products

Antibodies
CRM1 Antibody
CRM1 Antibody
Species: Hu, Mu, Primate, Rhesus Macaque
Applications: WB, Simple Western, ICC/IF, IHC-P, IP, PLA
Host: Rabbit Polyclonal
CRM1 Antibody
CRM1 Antibody
NB100-56493
Species: Hu, Bv, Ca, Pm, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
CRM1 Antibody
CRM1 Antibody
NBP2-33381
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
CRM1 Overexpression Lysate (N ...
CRM1 Overexpression Lysate (Native)
NBP2-10890
Applications: WB
Proteins
CRM1 Recombinant Protein
CRM1 Recombinant Protein
H00007514-P01
Species: Hu
Applications: WB, ELISA, PA
CRM1 Recombinant Protein Anti ...
CRM1 Recombinant Protein Antigen
NBP2-33381PEP
Species: Hu
Applications: AC
RNAi
CRM1 RNAi
CRM1 RNAi
H00007514-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Official Gene Symbol: XPO1 Gen Bank Accession Number: NP_003391 Gene ID: 7514 (human) Gene Map Locus: 2p16 (human) Nuclear transport receptors of karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-1, a human homolog of yeast CRM1, is a novel karyopherin export receptor that mediates leucine-rich NES-dependent protein export. It interacts with RanGTP through its Ran-binding domain and also with nucleoporins including Nup214, Nup50, Nup42 and Nup159 during the process of exporting NES-containing proteins. It mediates the export of many cellular and viral proteins and ribonucleoproteins including HIV Rev Protein, ERK3, PKI, IRF-5, Cyclin-B, MAPKK, MAPKAP kinase 2, Snurportin, Cap-binding protein, and certain U snRNAs. Reports suggest exportin-1 also has a role in the regulation of NFAT and AP-1.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 7514
Alternate Names
  • Exp1
  • DKFZp686B1823
  • Exportin-1 (required for chromosome region maintenance)
  • Chromosome region maintenance 1 protein homolog
  • exportin-1
  • exportin 1 (CRM1, yeast, homolog)
  • exp1
  • emb
  • yeast, homolog
  • exportin 1 (CRM1 homolog, yeast)

Research Areas for CRM1

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Stem Cell Markers

PTMs for CRM1

Learn more about PTMs related to CRM1.

Phosphorylation
Methylation
Dephosphorylation
Reduction
Cleavage
Oxidation

Bioinformatics Tool for CRM1

Discover related pathways, diseases and genes to CRM1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related CRM1 Blog Posts

Check out the latest blog posts on CRM1.
Survivin Acetylation: Affecting Apoptosis and Cancer
Survivin (BRIC5) is an inhibitor of apoptosis that also promotes cellular adaptation under stressful conditions and helps to regulate cell division. Recently, an antibody study by Dr. H Wang et al. at Brown University [PMID: 20826784] found that Survi...    Read more.
Read more CRM1 related blogs.