COX11 Products

Description

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. A related pseudogene has been found on chromosome 6. [provided by RefSeq]

Bioinformatics

Product By Gene ID	1353
Alternate Names	COX11 (yeast) homolog, cytochrome c oxidase assembly protein COX11 cytochrome c oxidase assembly homolog (yeast) COX11 homolog, cytochrome c oxidase assembly protein COX11P cytochrome c oxidase assembly protein COX11, mitochondrial cytochrome c oxidase subunit 11

Research Areas for COX11

Find related products by research area and learn more about each of the different research areas below.

Cancer
Signal Transduction