COX10 Products

Antibodies
COX10 Antibody
COX10 Antibody
NBP1-59554
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
COX10 Antibody
COX10 Antibody
NBP1-86323
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
COX10 Antibody
COX10 Antibody
NBP1-86322
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
COX10 Overexpression Lysate ( ...
COX10 Overexpression Lysate (Denat...
H00001352-T01
Species: Hu
Applications: WB
COX10 Overexpression Lysate ( ...
COX10 Overexpression Lysate (Native)
NBP2-08219
Applications: WB
Proteins
COX10 Recombinant Protein
COX10 Recombinant Protein
H00001352-P01
Species: Hu
Applications: WB, ELISA, PA
COX10 Partial Recombinant Pro ...
COX10 Partial Recombinant Protein
H00001352-Q01
Species: Hu
Applications: WB, ELISA, PA
COX10 Recombinant Protein Ant ...
COX10 Recombinant Protein Antigen
NBP1-86323PEP
Species: Hu
Applications: AC

Description

Cytochrome c oxidase assembly homolog 10 (COX10), also known as protoheme IX farnesyltransferase, mitochondrial, is a member of the UbiA prenyltransferase family. This protein converts protoheme 9 (IX) and farnexyl diphosphate to heme O. COX10 is required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. Mutations to the COX10 gene have been linked to cytochrome c oxidase deficiency also known as mitochondrial complex IV deficiency (MT-D4D), Charcot-Marie-Tooth type 1A (CMT1A) duplication, and hereditary neuropathy with liability to pressure palsies (HNPP) deletion. Leigh syndrome has also been associated with defects in the COX10 gene where bilateral symmetrical necrotic lesions appear in the subcortical brain regions.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 1352
Alternate Names
  • EC 2.5.1.-
  • cytochrome c oxidase assembly protein
  • protoheme IX farnesyltransferase, mitochondrial
  • COX10 (yeast) homolog, cytochrome c oxidase assembly protein (heme A:farnesyltransferase)
  • heme A: farnesyltransferase
  • Heme O synthase
  • cytochrome c oxidase subunit X
  • COX10 homolog, cytochrome c oxidase assembly protein, heme A:farnesyltransferase (yeast)

PTMs for COX10

Learn more about PTMs related to COX10.

Farnesylation
Phosphorylation
Hydroxylation
Oxidation

Bioinformatics Tool for COX10

Discover related pathways, diseases and genes to COX10. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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