This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. During maturation of the cornified layers, the protein undergoes a series of cleavages, which are thought to be required for desquamation. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6. [provided by RefSeq]
![Immunohistochemistry Corneodesmosin Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Corneodesmosin_AF5725_Immunohistochemistry_7196.jpg)
