Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
COPS6 is encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
10980 |
| Alternate Names |
- BMP2B
- BMP2B1
- BMP4
- COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
- COP9 signalosome complex subunit 6
- CSN6COP9 subunit 6 (MOV34 homolog, 34 kD)
- H_NH0506M12.12
- hVIP
- HVIP
- JAB1-containing signalosome subunit 6
- MOFC11
- MOV34 homolog
- MOV34 homolog, 34 kD
- MOV34-34KD
- SGN6
- Signalosome subunit 6
- Vpr-interacting protein
|
