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Collagen IV alpha 1 Products

Antibodies
Collagen IV alpha 1 Antibody ...
Collagen IV alpha 1 Antibody (HL13...
NBP3-25416
DR555RB) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the cell membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence Collagen IV alpha 1 Antibody (HL1351) - Azide and BSA Free
DR555RB) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the cell membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence Collagen IV alpha 1 Antibody (HL1351) - Azide and BSA Free
DR555RB) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the cell membrane. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence Collagen IV alpha 1 Antibody (HL1351) - Azide and BSA Free
Immunocytochemistry/ Immunofluorescence Collagen IV alpha 1 Antibody (HL1351) - Azide and BSA Free
Immunohistochemistry-Paraffin Collagen IV alpha 1 Antibody (HL1351) - Azide and BSA Free
Immunohistochemistry-Paraffin Collagen IV alpha 1 Antibody (HL1351) - Azide and BSA Free
Western Blot Collagen IV alpha 1 Antibody (HL1351) - Azide and BSA Free
Immunohistochemistry-Paraffin Collagen IV alpha 1 Antibody (HL1351) - Azide and BSA Free
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, COMET, mIF
Host: Rabbit Monoclonal
Collagen IV alpha 1 Antibody ...
Collagen IV alpha 1 Antibody (1106...
MAB11758
DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the extracellular space. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence Collagen IV alpha 1 Antibody (1106301) [Unconjugated]
DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the extracellular space. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence Collagen IV alpha 1 Antibody (1106301) [Unconjugated]
DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the extracellular space. Protocol available in COMET™ Panel Builder." class="big_lightbox" target="_blank"> Multiplex Immunofluorescence Collagen IV alpha 1 Antibody (1106301) [Unconjugated]
VCTS021). Tissue was stained using the HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007) and counterstained with hematoxylin (blue). Specific staining was localized to the basement membrane. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry Collagen IV alpha 1 Antibody (1106301) [Unconjugated]
VCTS021). Tissue was stained using the HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007) and counterstained with hematoxylin (blue). Specific staining was localized to the basement membrane. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry Collagen IV alpha 1 Antibody (1106301) [Unconjugated]
VCTS021). Tissue was stained using the HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007) and counterstained with hematoxylin (blue). Specific staining was localized to the basement membrane. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry Collagen IV alpha 1 Antibody (1106301) [Unconjugated]
Species: Hu
Applications: IHC, mIF
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 FAB11758U-100UG
Alexa Fluor 405 FAB11758V-100UG
Alexa Fluor 488 FAB11758G-100UG
Alexa Fluor 532 FAB11758X-100UG
Alexa Fluor 594 FAB11758T-100UG
Alexa Fluor 647 FAB11758R-100UG
Alexa Fluor 700 FAB11758N-100UG
Alexa Fluor 750 FAB11758S-100UG
Alexa Fluor Plus 405 FAB11758AFP405-100UG
Alexa Fluor Plus 488 FAB11758AFP488-100UG
Alexa Fluor Plus 555 FAB11758AFP555-100UG
Alexa Fluor Plus 594 FAB11758AFP594-100UG
Alexa Fluor Plus 647 FAB11758AFP647-100UG
Alexa Fluor Plus 680 FAB11758AFP680-100UG
Allophycocyanin FAB11758A
Biotin FAB11758B
CoraFluor 1 FAB11758CL1
DyLight 350 FAB11758D
DyLight 405 FAB11758E
DyLight 488 FAB11758K
DyLight 550 FAB11758L
DyLight 594 FAB11758M
DyLight 650 FAB11758W
DyLight 680 FAB11758Y
DyLight 755 FAB11758Z
FITC FAB11758F
HRP FAB11758H
Janelia Fluor 525 FAB11758JF525
Janelia Fluor 549 FAB11758I
Janelia Fluor 646 FAB11758J
Janelia Fluor 669 FAB11758JF669
PE FAB11758P
PerCP FAB11758C
mFluor Violet 450 SE FAB11758MFV450
mFluor Violet 500 SE FAB11758MFV500
mFluor Violet 610 SE FAB11758MFV610
Formulation Catalog # Availability Price  
Carrier Free MAB11758-100
Carrier Free MAB11758-SP
Collagen IV alpha 1 Antibody ...
Collagen IV alpha 1 Antibody [Unco...
AF6308
HAF016). A specific band was detected for Collagen IV a1 at approximately 95 kDa (as indicated) ref 1. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8." class="big_lightbox" target="_blank"> Western Blot Collagen IV alpha 1 Antibody [Unconjugated]
VC006). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to connective tissue. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank"> Immunohistochemistry Collagen IV alpha 1 Antibody [Unconjugated]
Species: Hu
Applications: WB, IHC
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 AF6308U-100UG
Alexa Fluor 405 AF6308V-100UG
Alexa Fluor 488 AF6308G-100UG
Alexa Fluor 532 AF6308X-100UG
Alexa Fluor 594 AF6308T-100UG
Alexa Fluor 647 AF6308R-100UG
Alexa Fluor 700 AF6308N-100UG
Alexa Fluor 750 AF6308S-100UG
Alexa Fluor Plus 405 AF6308AFP405-100UG
Alexa Fluor Plus 488 AF6308AFP488-100UG
Alexa Fluor Plus 555 AF6308AFP555-100UG
Alexa Fluor Plus 594 AF6308AFP594-100UG
Alexa Fluor Plus 647 AF6308AFP647-100UG
Alexa Fluor Plus 680 AF6308AFP680-100UG
Allophycocyanin AF6308A
Biotin AF6308B
CoraFluor 1 AF6308CL1
DyLight 350 AF6308D
DyLight 405 AF6308E
DyLight 488 AF6308K
DyLight 550 AF6308L
DyLight 594 AF6308M
DyLight 650 AF6308W
DyLight 680 AF6308Y
DyLight 755 AF6308Z
FITC AF6308F
HRP AF6308H
Janelia Fluor 525 AF6308JF525
Janelia Fluor 549 AF6308I
Janelia Fluor 646 AF6308J
Janelia Fluor 669 AF6308JF669
PE AF6308P
PerCP AF6308C
mFluor Violet 450 SE AF6308MFV450
mFluor Violet 500 SE AF6308MFV500
mFluor Violet 610 SE AF6308MFV610
Formulation Catalog # Availability Price  
Carrier Free AF6308-SP
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We have 25 Collagen IV alpha 1 Antibodies
ELISA Kits
Human Collagen IV alpha 1 ELI ...
Human Collagen IV alpha 1 ELISA Ki...
NBP2-75870
ELISA Human Collagen IV alpha 1 ELISA Kit (Colorimetric)
ELISA Human Collagen IV alpha 1 ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
Mouse Collagen IV alpha 1 ELI ...
Mouse Collagen IV alpha 1 ELISA Ki...
NBP2-75871
ELISA Mouse Collagen IV alpha 1 ELISA Kit (Colorimetric)
ELISA Mouse Collagen IV alpha 1 ELISA Kit (Colorimetric)
Species: Mu
Applications: ELISA
Human Collagen IV alpha 1 ELI ...
Human Collagen IV alpha 1 ELISA Ki...
NBP2-75867
ELISA Human Collagen IV alpha 1 ELISA Kit (Chemiluminescence)
ELISA Human Collagen IV alpha 1 ELISA Kit (Chemiluminescence)
Species: Hu
Applications: ELISA
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We have 6 Collagen IV alpha 1 ELISA Kits
Proteins
Recombinant Human Collagen IV ...
Recombinant Human Collagen IV alph...
11597-CL
7064-AB) with an ED50 of 85.0‑850 ng/mL." class="big_lightbox" target="_blank"> Binding Activity Collagen IV alpha 1 [Unconjugated]
SDS-Page Collagen IV alpha 1 [Unconjugated]
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Carrier Free 11597-CL-050
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We have 1 Collagen IV alpha 1 Protein

Description

Collagen IV is well suited to detect extracellular matrix proteins in normal as well as disease state tissues. Disruption of tissue organization is the hallmark of neoplasia. Malignant lesions can be distinguished from benign by examining the breakdown of basement membranes and loss of 3-dimensional architecture. Malignant cells are presumed to use matrix metalloproteases to degrade barriers created by the extracellular matrix which then allows metastasis to occur. Collagenases, stomelysins and gelatinases can collectively degrade all of the various components of the extracellular matrix, including fibrillar and non-fibrillar collagens and basement membrane glycoproteins.

Bioinformatics

Entrez
1282
Human
12826
Mouse
290905
Rat
Uniprot
P02462
Human
P02463
Mouse
Product By Gene ID 1282
Alternate Names
  • alpha-1 chain
  • arresten
  • COL4A1 NC1 domain
  • collagen alpha-1(IV) chain
  • collagen IV, alpha-1 polypeptide
  • collagen, type IV, alpha 1
  • Collagen-4
  • EC 3.4.23
  • EC 6.3.1.2

Research Areas for Collagen IV alpha 1

Find related products by research area and learn more about each of the different research areas below.

Cytoskeleton Markers
Extracellular Matrix
Stem Cell Markers

Related Collagen IV alpha 1 Blog Posts

Check out the latest blog posts on Collagen IV alpha 1.
Epithelial-Mesenchymal Transition (EMT) Markers
Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a...    Read more.
Read more Collagen IV alpha 1 related blogs.