CHMP4A Products

Description

CHMP4A (Chromatin-modifying protein 4a) belongs to the SNF7 family and functions as chromatin-modifying proteins. It probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. Also during HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins via the association of CHMP4 and a protein recruited by HIV-1 p6, which is present in viral Gag assembly and budding. CHMP4A expressed at higher level in heart, kidney, liver and skeletal muscle. Recombinant human CHMP4A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Bioinformatics

Product By Gene ID	29082
Alternate Names	C14orf123 charged multivesicular body protein 4a CHMP4 CHMP4a CHMP4B chromatin modifying protein 4A Chromatin-modifying protein 4a chromosome 14 open reading frame 123 FLJ61658 hSnf-1 HSPC134 hVps32-1 MGC142093 MGC142095 SHAX2 SNF7 homolog associated with Alix-2 Snf7 homologue associated with Alix 2 SNF7 SNF7-1 Vacuolar protein sorting-associated protein 32-1 VPS32-1 VPS32A