CHIP/STUB1 Products

Antibodies
CHIP/STUB1 Antibody
CHIP/STUB1 Antibody
NB100-77316
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, IP, WB (-)
Host: Rabbit Polyclonal
CHIP/STUB1 Antibody
CHIP/STUB1 Antibody
NBP1-30936
Species: Hu, Mu, Rt, Bv, Ch, RM
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
CHIP/STUB1 Antibody
CHIP/STUB1 Antibody
NB100-77315
Species: Hu, Mu
Applications: WB, IP, PLA
Host: Rabbit Polyclonal
Lysates
CHIP/STUB1 Overexpression Lys ...
CHIP/STUB1 Overexpression Lysate (...
H00010273-T01
Species: Hu
Applications: WB
CHIP/STUB1 Overexpression Lys ...
CHIP/STUB1 Overexpression Lysate (...
NBP2-07696
Applications: WB
Proteins
Recombinant Human CHIP/STUB1 ...
Recombinant Human CHIP/STUB1 Protein
NBC1-18849
Species: Hu
Applications: PAGE
CHIP/STUB1 Recombinant Protei ...
CHIP/STUB1 Recombinant Protein Ant...
NBP2-47510PEP
Species: Hu
Applications: AC
CHIP/STUB1 Recombinant Protei ...
CHIP/STUB1 Recombinant Protein Ant...
NBP2-47509PEP
Species: Hu
Applications: AC

Description

STUB1/CHIP is an E3 ubiquitin ligase and co-chaperone of heat-shock protein 70 (Hsp70). STUB1/CHIP interacts with Hsp70 to monitor protein folding and direct misfolded proteins for proteasomal degradation. It has been found to also associate with Hsp90 to remove phosphorylated protein tau, a protein that accumulates in the brains of Alzheimers and Down's syndrome patients. STUB1/CHIP has been reported to also have intrinsic chaperone activity and recognize non-native proteins in response to heat stress. In this way, STUB1/CHIP has been shown to be a direct chaperone for p53. Alternate names for STUB1/CHIP include carboxy terminus of Hsp70-interacting protein, STIP1 homology and U-box containing protein 1, CLL-associated antigen KW-8 antigen, serologically defined colon cancer antigen 7, heat shock protein A binding protein 2, NY-CO-7, HSPABP2, and SDCCAG7.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 10273
Alternate Names
  • Carboxy terminus of Hsp70-interacting protein
  • EC 6.3.2.-
  • Antigen NY-CO-7
  • serologically defined colon cancer antigen 7
  • UBOX1
  • heat shock protein A binding protein 2 (c-terminal)
  • SDCCAG7
  • E3 ubiquitin-protein ligase CHIP
  • NY-CO-7
  • STIP1 homology and U-box containing protein 1
  • HSPABP2
  • CHIPSTIP1 homology and U box-containing protein 1
  • CLL-associated antigen KW-8
  • STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase

Research Areas for CHIP/STUB1

Find related products by research area and learn more about each of the different research areas below.

Neuroscience

PTMs for CHIP/STUB1

Learn more about PTMs related to CHIP/STUB1.

Ubiquitination
Phosphorylation
Hydroxylation
Cleavage
Ubiquitinylation
Acetylation
Oxidation

Bioinformatics Tool for CHIP/STUB1

Discover related pathways, diseases and genes to CHIP/STUB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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