Chimaerin 2 Products

Description

Chimaerin 2 is a protein expressed in the brain and pancreas with two isoforms, measuring 468 and 332 amino acids in length with weights of approximately 54 and 38 kDa respectively. Chimaerin 2 functions as a GTP-ase activating protein for p21-rac, and a deficiency in this protein could lead to tumor progression. Current studies are being done on several diseases and disorders related to this protein including b-cell lymphomas, schizophrenia, sleeping sickness, insulin resistance, diabetic retinopathy, malignant glioma, nephropathy, spasticity, astrocytoma, and breast cancer. Chimaerin 2 has also been shown to have interactions with BAG6, NCK1, RAC1, ERBB3, and EIF3C in pathways such as the Rho GTPase cycle, signal transduction, and regulations of RAC1 activity pathways.

Bioinformatics

Product By Gene ID	1124
Alternate Names	ARHGAP3beta chimerin BCH beta-chimaerin Beta-chimerin chimerin (chimaerin) 2 MGC138360 Rho GTPase-activating protein 3 RhoGAP3 rho-GTPase-activating protein 3

Research Areas for Chimaerin 2

Find related products by research area and learn more about each of the different research areas below.

GPCR
Signal Transduction