CDK4 Products

Antibodies
CDK4 Antibody
CDK4 Antibody
Species: Hu, Mu, Bovine, Porcine, Rat, Sheep, Monkey
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
CDK4 Antibody
CDK4 Antibody
NBP2-32288
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
CDK4 Antibody (4F11)
CDK4 Antibody (4F11)
H00001019-M03
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Lysates
CDK4 Overexpression Lysate (D ...
CDK4 Overexpression Lysate (Denatu...
H00001019-T01
Species: Hu
Applications: WB
CDK4 Overexpression Lysate (N ...
CDK4 Overexpression Lysate (Native)
NBL1-09039
Applications: WB
Proteins
CDK4 Recombinant Protein
CDK4 Recombinant Protein
NBP2-22974
Species: Hu
Applications: PAGE
RNAi
CDK4 RNAi
CDK4 RNAi
H00001019-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
CDK4 RNAi
CDK4 RNAi
H00001019-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Cdk4 is encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 1019
Alternate Names
  • CMM3
  • EC 2.7.11
  • EC 2.7.11.22
  • melanoma cutaneous malignant, 3
  • Cell division protein kinase 4
  • PSK-J3cell division kinase 4
  • MGC14458
  • cyclin-dependent kinase 4

Research Areas for CDK4

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Core ESC-Like Genes
mTOR Pathway
Protein Kinase
Stem Cell Markers

Bioinformatics Tool for CDK4

Discover related pathways, diseases and genes to CDK4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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