CDC25B Products

Description

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.

Bioinformatics

Entrez	12531 Mouse 171103 Rat 994 Human
Uniprot	AAH06395 Human NP_068658 Human NP_068659 Human NP_068659.1 Human P30305 Human
Product By Gene ID	994
Alternate Names	CDC25HU2 cell division cycle 25 homolog B (S. cerevisiae) cell division cycle 25 homolog B (S. pombe) cell division cycle 25B Dual specificity phosphatase Cdc25B EC 3.1.3.48 M-phase inducer phosphatase 2

Research Areas for CDC25B

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Phospho-Specific