CD47 Products

Description

CD47 antigen, also known as integrin associated protein (IAP), has a very broad tissue distribution. CD47 is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. There are approximately 50.000 CD47 molecules per erythrocyte. The glycoprotein is deficient in erythrocytes of the rare Rh null phenotype. CD47 is a heavily N glycosylated cell membrane glycoprotein of apparent molecular weight 47-52 kDa. It may play a role as a signaltransducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells.

Bioinformatics

Entrez	29364 Rat 961 Human
Uniprot	NM_001777 Human NP_001768 Human NP_001768.1 Human NP_942088 Human Q08722 Human
Product By Gene ID	961
Alternate Names	antigen identified by monoclonal 1D8 Antigenic surface determinant protein OA3 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) CD47 antigen CD47 glycoprotein CD47 molecule IAPintegrin associated protein Integrin-associated protein leukocyte surface antigen CD47 MER6integrin-associated signal transducer OA3 Protein MER6 Rh-related antigen

Research Areas for CD47

Find related products by research area and learn more about each of the different research areas below.

Immunology
Signal Transduction