Catenin alpha 1 Products

Antibodies
Catenin alpha 1 Antibody (1G5 ...
Catenin alpha 1 Antibody (1G5)
NB100-74356
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IP
Host: Mouse Monoclonal
Catenin alpha 1 Antibody
Catenin alpha 1 Antibody
NBP2-15723
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Catenin alpha 1 Antibody
Catenin alpha 1 Antibody
NBP2-33456
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Catenin alpha 1 Overexpressio ...
Catenin alpha 1 Overexpression Lys...
NBL1-09575
Applications: WB
Proteins
Recombinant Human Catenin alp ...
Recombinant Human Catenin alpha 1 ...
H00001495-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human Catenin alp ...
Recombinant Human Catenin alpha 1 ...
H00001495-P01
Species: Hu
Applications: WB, ELISA, PA
Catenin alpha 1 Recombinant P ...
Catenin alpha 1 Recombinant Protei...
NBP2-33456PEP
Species: Hu
Applications: AC

Description

Cadherin and catenin compose cell adhesion complex and are indispensable for tight cell-cell adhesion. Dysfunction of this adhesion complex causes dissociation of cancer cells from primary tumor nodules, thus possibly contributing to cancer invasion and metastasis (1). At least three proteins (alpha, beta, and gamma catenin) comprise the cytoplasmic domain of the cadherin cell-cell adhesion complex. Data, with the reported structure of other catenin genes, suggest that vinculin and alpha-catenin generate a superfamily of proteins mediating membrane-cytoskeletal associations (2). Presenilin-1 (PS1) overexpression in human kidney cells enhances cell-cell adhesion and data show that PS1 incorporates into the cadherin/catenin adhesion system and regulates cell-cell adhesion. PS1 concentrates at intercellular contacts in epithelial tissue; in brain, it forms complexes with both E- and N-cadherin and concentrates at synaptic adhesions (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 1495
Alternate Names
  • FLJ52416
  • Cadherin-associated protein
  • FLJ36832
  • catenin alpha-1
  • catenin (cadherin-associated protein), alpha 1 (102kD)
  • cadherin-associated protein
  • Renal carcinoma antigen NY-REN-13
  • alphaE-catenin
  • Alpha E-catenin
  • alpha-catenin
  • CAP102
  • alpha-E-catenin
  • catenin (cadherin-associated protein), alpha 1, 102kDa

Research Areas for Catenin alpha 1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cellular Markers
Core ESC-Like Genes
Cytoskeleton Markers
Phospho-Specific
Stem Cell Markers

Bioinformatics Tool for Catenin alpha 1

Discover related pathways, diseases and genes to Catenin alpha 1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.