Species: Hu, Mu, Rt, Po, Bv, Ch, Eq
Applications: WB, ICC/IF, IHC
Host: Chicken Polyclonal
Hu, Mu, RtApplications:
Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Ialpha, Igamma, Idelta and Iepisilon, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2beta2 or an alphaalpha'beta2 structure. The a catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
Research Areas for Casein Kinase 1 alpha
Find related products by research area and learn more about each of the different research areas below.Protein KinaseWnt Signaling Pathway
PTMs for Casein Kinase 1 alpha
Learn more about PTMs related to Casein Kinase 1 alpha.Phosphorylation
Bioinformatics Tool for Casein Kinase 1 alpha
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