WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-PHost:
Species: Hu, Mu, Rt, Ca, Mk, Pm, Bt, Eq, Ha
Host: Rabbit Polyclonal
Host: Mouse Monoclonal
Applications: WB, ELISA, PA, PAGE, AP
Applications: WB, ELISA, PA, AP
Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P / Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.
|Product By Gene ID
- CX5testis-dominant CNR2 isoform CB2
- CB2cannabinoid receptor 2
- cannabinoid receptor 2 (macrophage)
Research Areas for Cannabinoid R2/CB2/CNR2
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Bioinformatics Tool for Cannabinoid R2/CB2/CNR2
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