Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Description
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Bioinformatics
| Product By Gene ID |
10753 |
| Alternate Names |
- calpain 9 (nCL-4)
- calpain 9
- calpain-9
- Digestive tract-specific calpain
- EC 3.4.22
- EC 3.4.22.54
- GC36
- NCL4
- nCL-4EC 3.4.22.-
- New calpain 4
- novel calpain large subunit-4
- Protein CG36
|
