Calcineurin A Products

Description

Calcineurin, a major soluble calmodulin binding protein in the brain, a Ca2+/calmodulin dependent serine/threonine protein phosphatase, with a relatively narrow substrate specificity. This metalloenzyme, also known as phosphatase 2B, is a heterodimer composed of a calmodulin binding, catalytic alpha subunit 61 kDa, calcineurin A) and calcium binding beta subunit (18 kDa, calcineurin B). The Ca2+ binding subunit, calcineurin B, is immunologically conserved from yeast to mammals. The presence of 2 different calcineurin B isoforms (beta 1 and beta 2) has been reported in rat testis. The catalytic subunit of calcineurin, calcineurin A, isolated from different tissues or different organisms, exhibits some immunological heterogeneity. Further, there are at least 2 isoforms of calcineurin A in bovine brain (alpha 1 and alpha 2, 61 and 59 kDa, respectively).

Bioinformatics

Product By Gene ID

5530

Alternate Names

calcineurin A alpha Calcineurin A Calmodulin-dependent calcineurin A subunit alpha isoform CALN CALNA CALNAcatalytic subunit, alpha isoform CAM-PRP catalytic subunit CNA CNA1 CNA1CALNA1 EC 3.1.3.16 PP2B PP3CA PPP2B PPP2BCCN1 PPP3CA protein phosphatase 2B, catalytic subunit, alpha isoform protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform(calcineurin A alpha) protein phosphatase 3, catalytic subunit, alpha isozyme serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

Research Areas for Calcineurin A

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Immunology
Protein Phosphatase
Wnt Signaling Pathway

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The role of HIF-1 Alpha signaling in the retina under hypoxic conditions Hypoxia inducible factor 1 (HIF-1) is a protein that plays an essential role in hypoxia, or low levels of cellular oxygen. HIF-1 is a heterodimeric protein that consists of a constitutively expressed beta subunit and oxygen related alpha subunit.  ...    Read more.

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