CACNA2D2 Products

Antibodies
CACNA2D2 Antibody (4E3)
CACNA2D2 Antibody (4E3)
H00009254-M12
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
CACNA2D2 Antibody (3A4)
CACNA2D2 Antibody (3A4)
H00009254-M05
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
CACNA2D2 Antibody
CACNA2D2 Antibody
NBP2-30044
Species: Hu, Mu
Applications: WB, ICC/IF, IHC-P
Host: Rabbit Polyclonal
Proteins
CACNA2D2 Partial Recombinant ...
CACNA2D2 Partial Recombinant Protein
H00009254-Q01
Species: Hu
Applications: WB, ELISA, PA
CACNA2D2 Recombinant Protein ...
CACNA2D2 Recombinant Protein Antigen
NBP1-81501PEP
Species: Hu
Applications: AC
RNAi
CACNA2D2 RNAi
CACNA2D2 RNAi
H00009254-R01
Species: Hu
CACNA2D2 RNAi
CACNA2D2 RNAi
H00009254-R02
Species: Hu

Description

The CACNA2D2 gene encodes a voltage-dependent calcium channel subunit alpha-2/delta-2 protein that exists in 5 isoforms: isoform 1: 1,150 amino acids long, 129 kDA; isoform 2: 1,143 amino acids long, 129 kDA; isoform 3: 1,145 amino acids long, 129 kDA; isoform 4: 1,076 amino acids long, 122 kDA; and isoform 5: 1,152 amino acids long, 130 kDA. These proteins are critical in calcium current density and in activation and inactivation kinetics of the calcium channel. Additionally, these proteins function as regulatory subunits for P/Q-type calcium channel, N-type, and L-type, as well as T-type. Overexpression of this gene triggers apoptosis. The CACNA2D2 gene participates in transcription of the CREB pathway, the caspase cascade, Fc-GammaR pathway, BMP and PDGF pathways, regulation of insulin secretion, and transmission across chemical synapses. It is known to interact with genes DLG4, CACNA1C, CACNA1D, CACNA1F, and YWHAB. The CACNA2D2 gene is associated with ataxia, seizures, lung cancer, and neuronitis.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 9254
Alternate Names
  • voltage-dependent calcium channel subunit alpha-2/delta-2
  • LUAC11.1
  • gene 26
  • CACNA2D
  • alpha 2 delta calcium channel subunit
  • KIAA0558Voltage-gated calcium channel subunit alpha-2/delta-2
  • calcium channel, voltage-dependent, alpha 2/delta subunit 2

PTMs for CACNA2D2

Learn more about PTMs related to CACNA2D2.

Methylation
Demethylation
Cleavage
Reduction
Acetylation
Gpi Anchoring

Bioinformatics Tool for CACNA2D2

Discover related pathways, diseases and genes to CACNA2D2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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