Hu, Mu, Rt, Av, Bv, Ca, Eq, Gp, RbApplications:
WB, ICC/IF, IHC, IHC-P, KDHost:
Hu, Mu, Rt, CaApplications:
WB, IHC, IHC-P, PEP-ELISAHost:
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Rabbit Monoclonal
WB, ELISA, PA, AP
Applications: WB, ELISA, PA, PAGE, AP
The c-Myb proto-oncogene is a 75 kDa protein involved in growth regulation and differentiation in many different cell types but it is predominantly expressed in immature hemopoietic cells where it plays an important role in cell proliferation. c-Myb activity is directly regulated by cyclin D1 and CDKs and it is believed that c-Myb activity is regulated during the cell cycle in hematopoietic cells (2). Disrupting c-myb function might, therefore, prove an effective therapeutic strategy for controlling leukemic cell growth (3). c-Myb binds to promoter sequences of genes such as c-Myc or Bcl-2 that are expressed in cutaneous T-cell lymphoma.
Research Areas for c-Myb
Find related products by research area and learn more about each of the different research areas below.CancerPhospho-Specific
Bioinformatics Tool for c-Myb
Discover related pathways, diseases and genes to c-Myb. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.