BPTF/FALZ Products

Antibodies
BPTF/FALZ Antibody
BPTF/FALZ Antibody
NB100-41418
Species: Hu, Primate
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
BPTF/FALZ Antibody
BPTF/FALZ Antibody
NBP1-84756
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
BPTF/FALZ Antibody (2F10)
BPTF/FALZ Antibody (2F10)
NBP2-37608
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Proteins
BPTF/FALZ Recombinant Protein ...
BPTF/FALZ Recombinant Protein Antigen
NBP1-84756PEP
Species: Hu
Applications: AC
RNAi
BPTF/FALZ RNAi
BPTF/FALZ RNAi
H00002186-R02
Species: Hu
BPTF/FALZ RNAi
BPTF/FALZ RNAi
H00002186-R01
Species: Hu

Description

FALZ/BPTF is a histone-binding component of NURF (nucleosome remodeling factor), a complex that catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. This gene was identified in brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), containing a DNA-binding domain, a zinc finger motif, and a C-terminal bromodomain, suggested it might play a role in the regulation of transcription during proliferation. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. This protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 2186
Alternate Names
  • Fetal Alz-50 clone 1 protein
  • EC 6.2.1.5
  • Bromodomain and PHD finger-containing transcription factor
  • EC 3.6.1
  • NURF301
  • FALZnucleosome-remodeling factor subunit BPTF
  • Fetal Alzheimer antigennucleosome remodeling factor, large subunit
  • FAC1fetal Alz-50 reactive clone 1
  • bromodomain and PHD domain transcription factor
  • bromodomain PHD finger transcription factor

PTMs for BPTF/FALZ

Learn more about PTMs related to BPTF/FALZ.

Methylation
Acetylation
Demethylation
Carboxylation

Bioinformatics Tool for BPTF/FALZ

Discover related pathways, diseases and genes to BPTF/FALZ. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.