BIN1 Products

Antibodies
BIN1 Antibody
BIN1 Antibody
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
BIN1 Antibody
BIN1 Antibody
NBP1-89102
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
BIN1 Antibody (3B6F10)
BIN1 Antibody (3B6F10)
NBP2-61714
Species: Hu, Mu
Applications: WB, ELISA, Flow, IHC, IHC-P
Host: Mouse Monoclonal
Lysates
BIN1 Overexpression Lysate
BIN1 Overexpression Lysate
NBP2-05567
Species: Hu
Applications: WB
BIN1 Overexpression Lysate
BIN1 Overexpression Lysate
NBP2-05566
Species: Hu
Applications: WB
BIN1 Overexpression Lysate
BIN1 Overexpression Lysate
NBP2-04422
Species: Hu
Applications: WB
Proteins
Recombinant Human BIN1 Protei ...
Recombinant Human BIN1 Protein
NBP1-45322
Species: Hu
Applications: WB, PAGE
BIN1 Recombinant Protein Anti ...
BIN1 Recombinant Protein Antigen
NBP1-89102PEP
Species: Hu
Applications: AC
BIN1 Recombinant Protein Anti ...
BIN1 Recombinant Protein Antigen
NBP1-89103PEP
Species: Hu
Applications: AC

Description

BIN1 encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 274
Alternate Names
  • myc box-dependent-interacting protein 1
  • Amphiphysin-like protein
  • box dependant MYC interacting protein 1
  • Amphiphysin II
  • SH3P9
  • MGC10367
  • AMPH2
  • AMPHLDKFZp547F068
  • bridging integrator 1Box-dependent myc-interacting protein 1

Research Areas for BIN1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Tumor Suppressors

PTMs for BIN1

Learn more about PTMs related to BIN1.

Phosphorylation
Methylation
Cleavage
Biotinylation

Bioinformatics Tool for BIN1

Discover related pathways, diseases and genes to BIN1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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