BIN1 Products

Antibodies
BIN1 Antibody
BIN1 Antibody
NBP1-46170
Species: Hu, Pm, RM
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
BIN1 Antibody (2F11)
BIN1 Antibody (2F11)
NBP2-21675
Species: Hu, Mu
Applications: WB, ELISA, IHC, IHC-P, IP
Host: Mouse Monoclonal
BIN1 Antibody
BIN1 Antibody
NBP1-89102
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
BIN1 Overexpression Lysate (D ...
BIN1 Overexpression Lysate (Denatu...
H00000274-T01
Species: Hu
Applications: WB
BIN1 Overexpression Lysate (N ...
BIN1 Overexpression Lysate (Native)
NBP2-09976
Applications: WB
BIN1 Overexpression Lysate (N ...
BIN1 Overexpression Lysate (Native)
NBP2-04422
Applications: WB
Proteins
BIN1 Recombinant Protein Anti ...
BIN1 Recombinant Protein Antigen
NBP1-89103PEP
Species: Hu
Applications: AC
BIN1 Recombinant Protein Anti ...
BIN1 Recombinant Protein Antigen
NBP1-89102PEP
Species: Hu
Applications: AC
Recombinant Human BIN1 Protei ...
Recombinant Human BIN1 Protein
NBP1-45322
Species: Hu
Applications: PAGE
RNAi
BIN1 RNAi
BIN1 RNAi
H00000274-R10
Species: Hu
Applications: RNAi, RNAi SP
BIN1 RNAi
BIN1 RNAi
H00000274-R08
Species: Hu
Applications: RNAi, RNAi SP
BIN1 RNAi
BIN1 RNAi
H00000274-R09
Species: Hu
Applications: RNAi, RNAi SP

Description

BIN1 encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 274
Alternate Names
  • myc box-dependent-interacting protein 1
  • Amphiphysin-like protein
  • box dependant MYC interacting protein 1
  • Amphiphysin II
  • SH3P9
  • MGC10367
  • AMPH2
  • AMPHLDKFZp547F068
  • bridging integrator 1Box-dependent myc-interacting protein 1

Research Areas for BIN1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Tumor Suppressors

PTMs for BIN1

Learn more about PTMs related to BIN1.

Phosphorylation
Methylation
Cleavage
Biotinylation

Bioinformatics Tool for BIN1

Discover related pathways, diseases and genes to BIN1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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