BCAP31 Products

Description

BAP31 (B Cell Receptor Associated Protein, 28 kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo and hetero oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL2/BCLXL associated protein. In the C terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.

Bioinformatics

Entrez	10134 Human
Uniprot	NM_005745 Human NP_001132913 Human NP_001132929 Human NP_005736 Human NP_005736. Human NP_005736.3 Human P51572 Human
Product By Gene ID	10134
Alternate Names	Bap31,6C6-AG BAP31DXS1357ECDM B-cell receptor-associated protein 31 BCR-associated protein 31 BCR-associated protein Bap31,6C6-AG tumor-associated antigen p28 Bap31,6C6-Ag p28 Protein CDM

Research Areas for BCAP31

Find related products by research area and learn more about each of the different research areas below.

Apoptosis