Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Hu, Bv, Ha, Pm, Mu(-), Rt(-)Applications:
WB, ELISA, ICC/IF, IHC, IHC-Fr, IPHost:
Applications: WB, ELISA, PA, PAGE, AP
Applications: WB, ELISA, PA, AP
BAP31 (B Cell Receptor Associated Protein, 28 kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo and hetero oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL2/BCLXL associated protein. In the C terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.
Research Areas for BCAP31
Find related products by research area and learn more about each of the different research areas below.Apoptosis
Bioinformatics Tool for BCAP31
Discover related pathways, diseases and genes to BCAP31. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.