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BAMBI encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis.
![Immunohistochemistry BAMBI/NMA Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/BAMBI_AF921_Immunohistochemistry_17593.jpg)
![Sandwich ELISA BAMBI/NMA Antibody Pair [HRP]](http://images.novusbio.com/fullsize/BAMBI-NMA-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79317-img0001.jpg)
