BACE-2 Products

Antibodies
BACE-2 Antibody (391017) [Unc ...
BACE-2 Antibody (391017) [Unconjug...
MAB4097
Species: Hu
Applications: IHC
Host: Rat Monoclonal
BACE-2 Antibody
BACE-2 Antibody
AF4097
Species: Hu
Applications: WB, IP
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
BACE-2 Antibody
BACE-2 Antibody
16520002
Species: Hu
Applications: ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
BACE-2 Overexpression Lysate ...
BACE-2 Overexpression Lysate (Native)
NBP2-09973
Applications: WB
BACE-2 Overexpression Lysate ...
BACE-2 Overexpression Lysate (Native)
NBP2-07491
Applications: WB
BACE-2 Overexpression Lysate ...
BACE-2 Overexpression Lysate (Native)
NBP2-05612
Applications: WB
Proteins
BACE-2 Partial Recombinant Pr ...
BACE-2 Partial Recombinant Protein
H00025825-Q01
Species: Hu
Applications: WB, ELISA, PA
BACE-2 Peptide
BACE-2 Peptide
NBP1-77308PEP
Species: Hu
Applications: AC
BACE-2 Peptide
BACE-2 Peptide
NBP1-77309PEP
Species: Hu
Applications: AC
RNAi
BACE-2 RNAi
BACE-2 RNAi
H00025825-R02
Species: Hu
BACE-2 RNAi
BACE-2 RNAi
H00025825-R01
Species: Hu
BACE-2 RNAi
BACE-2 RNAi
H00025825-R03
Species: Hu

Description

BACE2 (Memapsin 1) is a membrane-bound aspartic protease that is highly homologous with BACE1 (Memapsin 2). While BACE1 processes the amyloid precursor protein (APP) at a key step in generating the beta-amyloid peptide and presumably causes Alzheimer's disease (AD), BACE2 has not been demonstrated to be directly involved in APP processing, and its physiological functions remain to be determined. In vivo, BACE2 is expressed as a precursor protein containing pre-, pro-, protease, transmembrane, and cytosolic domains/peptides.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 25825
Alternate Names
  • EC 3.4.23
  • ASP21
  • Theta-secretase
  • ASP1
  • Memapsin-1
  • AEPLC
  • EC 3.4.23.45
  • Membrane-associated aspartic protease 1
  • transmembrane aspartic proteinase Asp1
  • Down region aspartic protease
  • theta-secretase
  • Beta-site APP cleaving enzyme 2
  • memapsin-1
  • Beta-site amyloid precursor protein cleaving enzyme 2
  • Down syndrome region aspartic protease
  • Aspartyl protease 1
  • beta-site amyloid beta A4 precursor protein-cleaving enzyme 2
  • Aspartic-like protease 56 kDa
  • beta-secretase 2
  • Asp 1
  • beta secretase 2
  • CEAP1
  • DRAPBAE2
  • beta-site APP-cleaving enzyme 2, EC 3.4.2310ALP5656 kDa aspartic-like protease
  • beta-site APP-cleaving enzyme 2

Research Areas for BACE-2

Find related products by research area and learn more about each of the different research areas below.

Neuroscience

PTMs for BACE-2

Learn more about PTMs related to BACE-2.

Cleavage
Glycosylation
Phosphorylation
Reduction
Palmitoylation
Deglycosylation

Bioinformatics Tool for BACE-2

Discover related pathways, diseases and genes to BACE-2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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