B7-H4 Products

Antibodies
B7-H4 Antibody
B7-H4 Antibody
NBP2-30536
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
B7-H4 Antibody [Unconjugated] ...
B7-H4 Antibody [Unconjugated]
AF2154
Species: Hu, Mu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
B7-H4 Antibody (H74)
B7-H4 Antibody (H74)
NBP1-43273
Species: Hu
Applications: Flow
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Lysates
B7-H4 Overexpression Lysate ( ...
B7-H4 Overexpression Lysate (Native)
NBL1-17768
Applications: WB
Proteins
Recombinant Mouse B7-H4 His-t ...
Recombinant Mouse B7-H4 His-tag Pr...
2154-B7
Species: Mu
Applications: BA
Recombinant Human B7-H4 Prote ...
Recombinant Human B7-H4 Protein Fc...
8870-B7
Species: Hu
Applications: BA
Recombinant Mouse B7-H4 Fc Ch ...
Recombinant Mouse B7-H4 Fc Chimera...
4206-B7
Species: Mu
Applications: BA

Description

B7H4 is a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity. Although B7H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production. B7H4 deficient mice are only minimally affected, thus suggesting B7H4 is important in the fine tuning of the T-cell mediated immune response. B7H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells. Aberrant expression has been associated with cancers of the lung, breast and ovary in humans. B7H4 could be a useful prognostic marker in Renal Cell Carcinoma (RCC). There are three different isoforms.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 79679
Alternate Names
  • Protein B7S1
  • Immune costimulatory protein B7-H4
  • V-set domain-containing T-cell activation inhibitor 1
  • FLJ22418
  • T cell costimulatory molecule B7x
  • B7-H4
  • B7XPRO1291
  • B7S1VCTN1
  • B7H4T-cell costimulatory molecule B7x
  • B7h.5
  • V-set domain containing T cell activation inhibitor 1

PTMs for B7-H4

Learn more about PTMs related to B7-H4.

Phosphorylation
Glycosylation

Bioinformatics Tool for B7-H4

Discover related pathways, diseases and genes to B7-H4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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