B4GALT3 Products

Description

Several oligosaccharide structures and protein glycoconjugate types are found in nature. Homologous glycosyltransferase (GT) gene families catalyze the formation of glycosidic linkages. The beta-1,3 galactosyltransferase(beta3GalT) gene family encodes a set of type II transmembrane glycoproteins that are catalytically diverse and use different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine ) to catalyze the addition of an activated monosaccharide to a terminal lactose. The protein coding sequences for beta-1,3-Gal-T genes comprise a single exon and are distantly related to the Drosophila Brainiac gene. The beta-1,4-galactosyltransferase (beta4GalT) gene family encodes type II membrane-bound glycoproteins that show exclusive specificity for the donor substrate, UDP-galactose. beta-1,4Gal-T genes transfer galactose in a beta-1,4 linkage to similar acceptor sugars; each gene has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures.

Bioinformatics

Entrez	8703 Human
Uniprot	NM_003779 Human NP_003770.1 Human O60512 Human
Product By Gene ID	8703
Alternate Names	b4Gal-T3 beta-1,4-galactosyltransferase 3 Beta-1,4-GalTase 3 Beta4Gal-T3 beta4Gal-T3 beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 3 EC 2.4.1.- UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3 UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3

Research Areas for B4GALT3

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Lipid and Metabolism