Axin-2 Products

Antibodies
Axin-2 Antibody
Axin-2 Antibody
NBP1-76526
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Axin-2 Antibody (354214) [Unc ...
Axin-2 Antibody (354214) [Unconjug...
MAB6078
Species: Hu
Applications: ICC
Host: Mouse Monoclonal
Axin-2 Antibody
Axin-2 Antibody
24830002
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Axin-2 Overexpression Lysate ...
Axin-2 Overexpression Lysate (Native)
NBL1-07868
Applications: WB
Proteins
Axin-2 Partial Recombinant Pr ...
Axin-2 Partial Recombinant Protein
H00008313-Q01
Species: Hu
Applications: WB, ELISA, PA
Axin-2 Recombinant Protein
Axin-2 Recombinant Protein
H00008313-P01
Species: Hu
Applications: WB, ELISA, PA
Axin-2 Partial Recombinant Pr ...
Axin-2 Partial Recombinant Protein
H00008313-Q02
Species: Hu
Applications: WB, ELISA, PA

Description

The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 8313
Alternate Names
  • AXIL
  • Conductin
  • Axis inhibition protein 2
  • Axil
  • Axin-like protein
  • conductin
  • MGC126582
  • axin-2
  • DKFZp781B0869
  • MGC10366
  • axin 2

Research Areas for Axin-2

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction
Wnt Signaling Pathway

Bioinformatics Tool for Axin-2

Discover related pathways, diseases and genes to Axin-2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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