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HAF005). Specific bands were detected for Autoimmune Regulator/AIRE at approximately 70 and 48 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
MAB006, open histogram), followed by Phycoerythrin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0105B). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin." class="big_lightbox" target="_blank">
Species: Mu Applications: WB, CyTOF-ready, Flow Host: Rat Monoclonal
AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
![Western Blot Autoimmune Regulator/AIRE Antibody (609930) [Unconjugated]](http://images.novusbio.com/images/antibody/Autoimmune_Regulator_MAB6184_Western_Blot_10455.jpg)
![Intracellular Staining by Flow Cytometry Autoimmune Regulator/AIRE Antibody (609930) [Unconjugated]](http://images.novusbio.com/images/antibody/Autoimmune_Regulator_MAB6184_Flow_Cytometry_11942.jpg)
