ATP6V1G3 Products

Description

ATP6V1G3 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	127124 Human
Uniprot	NP_573569 Human NP_573569.1 Human NP_579872 Human
Product By Gene ID	127124
Alternate Names	ATPase, H+ transporting, lysosomal 13kD, V1 subunit G isoform 3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 H+ transporting, lysosomal (vacuolar proton pump) subunit G3 MGC119810 MGC119813 vacuolar ATP synthase subunit G 3 vacuolar proton pump G subunit 3 Vacuolar proton pump subunit G 3 vacuolar proton pump, subunit G3 V-ATPase 13 kDa subunit 3 V-ATPase G subunit 3 V-ATPase G3 subunit V-ATPase subunit G 3 V-type proton ATPase subunit G 3