ATP6AP1 Products

Description

ATP6AP1 encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules.

Bioinformatics

Entrez	537 Human
Uniprot	NM_001183 Human NP_001174 Human NP_001174.2 Human Q15904 Human
Product By Gene ID	537
Alternate Names	16A Ac45 ATP6IP1V-ATPase subunit S1 ATP6S1ORF ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1 ATPase, H+ transporting, lysosomal accessory protein 1 H+ transporting, lysosomal interacting protein 1 H-ATPase subunit MGC129781 Protein XAP-3 Vacuolar proton pump subunit S1 VATPS1V-ATPase Ac45 subunit V-type proton ATPase subunit S1 XAP-3 XAP3V-ATPase S1 accessory protein